117284-94-3Relevant academic research and scientific papers
Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins
Cowden,Halladay,Cunningham,Hunt,Clark
, p. 1818 - 1822 (2007/10/02)
A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.
