1173021-09-4

Basic information

• Product Name: Clenproperol
• Synonyms: Clenproperol-d7;1-(4-amino-3,5-dichlorophenyl)-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)ethanol;Clenproperol-d6
• CAS NO: 1173021-09-4
• Molecular Formula: C11H16Cl2N2O
• Molecular Weight: 263.16354
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Amines, Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1173021-09-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 109-111°C
• Appearance: /
• Storage Temp.: -20?C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Clenproperol(CAS DataBase Reference)
• NIST Chemistry Reference: Clenproperol(1173021-09-4)
• EPA Substance Registry System: Clenproperol(1173021-09-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 1173021-09-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 1173021-09-4 differently. You can refer to the following data:
1. A labelled related drug
2. A labelled related drug of Clenbuterol (C569998), a β-agonist which can be used as a growth promoter in farm animals.

Upstream product

• 608-31-1 2,6-Dichloroaniline 
• 37148-48-4 1-(4-amino-3,5-dichlorophenyl)-1-ethanone 
• 666-52-4 [⁽²⁾H₆]acetone 
• 38339-07-0 4-amino-α-(aminomethyl)-3,5-dichlorobenzenemethanol 
• 37148-47-3 1-(4-amino-3,5-dichlorophenyl)-2-bromoethan-1-one 

Relevant articles and documents

Preparation method of stable isotope labeled clenproperol

The invention relates to a preparation method of stable isotope labeled clenproperol, which comprises the following steps: by taking 4-amino-3,5-dichloroacetophenone (II) as a raw material, carrying out bromination reaction to prepare a compound (III), then carrying out improved Gabriel synthesis reaction, namely amination reaction with sodium diformamide to obtain a compound (IV), then carrying out hydrolysis and reduction to obtain a compound (VI), and carrying out reductive amination reaction to generate a target compound (I). The preparation method disclosed by the invention is reasonable in process design, low in raw material price, controllable in experimental process and simple and convenient to operate, various required labeled compounds such as D-labeled, 13C-labeled or D/13C double-labeled compounds can be conveniently synthesized, and the prepared target product is high in purity, can be used as an internal standard substance in the field of food safety detection, and has important practical application value.