1173021-73-2 Usage
Description
Salbutamol-d9 is intended for use as an internal standard for the quantification of salbutamol (Item Nos. 21003 | 23991) by GC- or LC-MS. Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). It is selective for β2-ARs over β1- and β3-ARs (Kds = 46.8 and 21.9 μM, respectively). Salbutamol (25-50 μg/kg, i.v.) reduces acetylcholine-induced bronchospasm in anesthetized guinea pigs. It also reduces response of bronchial muscle to efferent vagal stimulation in anesthetized cats and dogs when administered at doses ranging from 1 to 2.5 and 10 to 20 μg/kg, respectively. Nebulized salbutamol reduces transpulmonary pressure in recurrent airway obstruction-affected horses (EC50 = 39.7 μg). Formulations containing salbutamol have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Chemical Properties
Off-White to Pale Yellow Solid
Uses
Different sources of media describe the Uses of 1173021-73-2 differently. You can refer to the following data:
1. A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic.
2. RAC ALBUTEROL-D9 is a labelled β2-adrenoceptor agonist,it is intended for use as an internal standard for the quantification of Albuterol by GC- or LC-mass spectrometry.
3. A labeled ?-adrenoceptor agonist
Check Digit Verification of cas no
The CAS Registry Mumber 1173021-73-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,3,0,2 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1173021-73:
(9*1)+(8*1)+(7*7)+(6*3)+(5*0)+(4*2)+(3*1)+(2*7)+(1*3)=112
112 % 10 = 2
So 1173021-73-2 is a valid CAS Registry Number.
