117309-80-5 Usage
Uses
Used in Biochemical Research:
5-Methyl-Uridine-5'-monophosphate, disodium salt is used as a substrate in enzyme-catalyzed reactions for studying the mechanisms of RNA modification and the function of methyltransferases, contributing to a deeper understanding of RNA biology and its role in various cellular processes.
Used in Molecular Biology Research:
In molecular biology, 5-Methyl-Uridine-5'-monophosphate, disodium salt is used in the synthesis of labeled nucleotides, which are essential for tracking and analyzing nucleic acid sequences, thereby aiding in the development of diagnostic and therapeutic strategies in genomics and related fields.
Used in Pharmaceutical Development:
5-Methyl-Uridine-5'-monophosphate, disodium salt may also be utilized in the development of drugs targeting RNA modification pathways, potentially leading to treatments for diseases associated with aberrant RNA function, although this application would require further exploration and validation in pharmaceutical research settings.
Check Digit Verification of cas no
The CAS Registry Mumber 117309-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,3,0 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 117309-80:
(8*1)+(7*1)+(6*7)+(5*3)+(4*0)+(3*9)+(2*8)+(1*0)=115
115 % 10 = 5
So 117309-80-5 is a valid CAS Registry Number.
117309-80-5Relevant academic research and scientific papers
Synthesis and Cytostatic and Antiviral Activities of 1-β-D-Ribofuranosyl-5-alkylcytosine (5-Alkylcytidine) Cyclic 3',5'-Monophosphates
Beres, Jozsef,Bentrude, Wesley G.,Oetvoes, Laszlo,Balzarini, Jan,Clercq, Erik De
, p. 224 - 228 (2007/10/02)
A series of 5-alkylcytidines and their 5'-monophosphates and cyclic 3',5'-monophosphates have been synthesized and evaluated for antiviral and antitumor activity.The 5-alkyl cyclic nucleotides were not cytostatic (ID 50 > 200 μg/mL) against leukemia L1210 cells and a deoxycytidine kinase-deficient subline thereof.Certain of the corresponding nucleosides and their 5'-monophosphates did show activity within the range of 35-162 μg/mL, as did the unsubstituted cytidine cyclic 3',5'-monophosphate.No antiviral activity was found for any of the compounds at 400 μg/mL.A drug design rationale for utilization of 5-alkylcytidines based on their potential conversion to biologically active 5-alkyl-2'-deoxyuridines is not supported by these experimental findings.
