117309-80-5 Usage
General Description
5-Methyl-Uridine-5'-monophosphate, disodium salt is a chemical compound that is used in various applications in the field of biochemistry and molecular biology. It is a derivative of uridine, a nucleoside that is essential for the synthesis of RNA and DNA. 5-Methyl-Uridine-5'-monophosphate, disodium salt is commonly used as a substrate in enzyme-catalyzed reactions to study the mechanisms of RNA modification and the function of methyltransferases. In addition, it is also used in the synthesis of labeled nucleotides for use in molecular biology research. The disodium salt form of this compound makes it more water-soluble and easier to handle in laboratory settings. Overall, 5-Methyl-Uridine-5'-monophosphate, disodium salt plays a crucial role in advancing our understanding of nucleic acid biochemistry and has important applications in various research fields.
Check Digit Verification of cas no
The CAS Registry Mumber 117309-80-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,3,0 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 117309-80:
(8*1)+(7*1)+(6*7)+(5*3)+(4*0)+(3*9)+(2*8)+(1*0)=115
115 % 10 = 5
So 117309-80-5 is a valid CAS Registry Number.
117309-80-5Relevant articles and documents
Synthesis and Cytostatic and Antiviral Activities of 1-β-D-Ribofuranosyl-5-alkylcytosine (5-Alkylcytidine) Cyclic 3',5'-Monophosphates
Beres, Jozsef,Bentrude, Wesley G.,Oetvoes, Laszlo,Balzarini, Jan,Clercq, Erik De
, p. 224 - 228 (2007/10/02)
A series of 5-alkylcytidines and their 5'-monophosphates and cyclic 3',5'-monophosphates have been synthesized and evaluated for antiviral and antitumor activity.The 5-alkyl cyclic nucleotides were not cytostatic (ID 50 > 200 μg/mL) against leukemia L1210 cells and a deoxycytidine kinase-deficient subline thereof.Certain of the corresponding nucleosides and their 5'-monophosphates did show activity within the range of 35-162 μg/mL, as did the unsubstituted cytidine cyclic 3',5'-monophosphate.No antiviral activity was found for any of the compounds at 400 μg/mL.A drug design rationale for utilization of 5-alkylcytidines based on their potential conversion to biologically active 5-alkyl-2'-deoxyuridines is not supported by these experimental findings.
