117309-93-0

Basic information

• Product Name: 4-amino-1-[(6R,7R)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-5-hexylpyrimidin-2(1H)-one
• CAS NO: 117309-93-0
• Molecular Formula: C₁₅H₂₄N₃O₇P
• Molecular Weight: 389.3407
• Mol File: 117309-93-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 593.7°C at 760 mmHg
• Flash Point: 312.9°C
• Density: 1.7g/cm³
• Vapor Pressure: 1.43E-16mmHg at 25°C
• Refractive Index: 1.686
• CAS DataBase Reference: 4-amino-1-[(6R,7R)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-5-hexylpyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-1-[(6R,7R)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-5-hexylpyrimidin-2(1H)-one(117309-93-0)
• EPA Substance Registry System: 4-amino-1-[(6R,7R)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-5-hexylpyrimidin-2(1H)-one(117309-93-0)

Safety Data

• Hazardous Substances Data: 117309-93-0(Hazardous Substances Data)

Upstream product

• 117309-85-0 5-n-hexylcytidine 5'-monophosphate diammonium salt 
• 90012-90-1 5-n-hexyl-cytidine 

Relevant articles and documents

Synthesis and Cytostatic and Antiviral Activities of 1-β-D-Ribofuranosyl-5-alkylcytosine (5-Alkylcytidine) Cyclic 3',5'-Monophosphates

A series of 5-alkylcytidines and their 5'-monophosphates and cyclic 3',5'-monophosphates have been synthesized and evaluated for antiviral and antitumor activity.The 5-alkyl cyclic nucleotides were not cytostatic (ID 50 > 200 μg/mL) against leukemia L1210 cells and a deoxycytidine kinase-deficient subline thereof.Certain of the corresponding nucleosides and their 5'-monophosphates did show activity within the range of 35-162 μg/mL, as did the unsubstituted cytidine cyclic 3',5'-monophosphate.No antiviral activity was found for any of the compounds at 400 μg/mL.A drug design rationale for utilization of 5-alkylcytidines based on their potential conversion to biologically active 5-alkyl-2'-deoxyuridines is not supported by these experimental findings.