117322-84-6Relevant articles and documents
Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels
Amendoeira, Fábio Coelho,Araújo, Jo?o Felipe Garcia,Carvalho, Katharinne Ingrid Moraes de,Costa, Jorge Carlos Santos da,Coutinho, Diego de Sá,Faria, Robson Xavier,Ferrero, Maximiliano R.,Fonseca, Laís Bastos da,Martins, Marco Aurélio,Pereira, Heliana Martins,Pinto, Douglas Pereira,Santos-Filho, Osvaldo Andrade,Silva, Aline C. A.,Silva, Diego Medeiros da,Silva, Emerson Teixeira da,Silva, Letícia Vallim da,Silveira, Gabriel Parreiras Estolano,Souza, Marcus Vinicius Nora de
, (2020)
Existing evidence suggests that the local anaesthetic mexiletine can be beneficial for patients with asthma. However, caution is required since anaesthesia of the airways inhibits protective bronchodilator neuronal reflexes, limiting applications in condi
