Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1173243-36-1

N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1173243-36-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1173243-36-1 Structure

  • Basic information

    1. Product Name: N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide
    2. Synonyms: N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide
    3. CAS NO:1173243-36-1
    4. Molecular Formula:
    5. Molecular Weight: 415.602
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1173243-36-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide(1173243-36-1)
    11. EPA Substance Registry System: N,N-diethyl-N′-(tritylcarbamothioyl)acetimidamide(1173243-36-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1173243-36-1(Hazardous Substances Data)

1173243-36-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1173243-36-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,3,2,4 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1173243-36:
(9*1)+(8*1)+(7*7)+(6*3)+(5*2)+(4*4)+(3*3)+(2*3)+(1*6)=131
131 % 10 = 1
So 1173243-36-1 is a valid CAS Registry Number.

1173243-36-1Relevant articles and documents

Investigations on substituted (2-aminothiazol-5-yl)(imidazo[1,2-a]pyridin-3-yl)methanones for the treatment of Alzheimer's disease

Sagar, Sneha R.,Singh, Devendra Pratap,Das, Rajesh D.,Panchal, Nirupa B.,Sudarsanam, Vasudevan,Nivsarkar, Manish,Vasu, Kamala K.

, (2021)

Alzheimer's disease (AD) is a neurodegenerative disease majorly affecting old age populations. Various factors that affect the progression of the disease include, amyloid plaque formation, neurofibrillary tangles, inflammation, oxidative stress, etc. Here

Pharmacological investigation of quinoxaline-bisthiazoles as multitarget-directed ligands for the treatment of Alzheimer's disease

Sagar, Sneha R.,Singh, Devendra Pratap,Das, Rajesh D.,Panchal, Nirupa B.,Sudarsanam, Vasudevan,Nivsarkar, Manish,Vasu, Kamala K.

, (2019/06/08)

Alzheimer's disease (AD) is the most prevalent disease of old age leading to dementia. Complex AD pathogenesis involves multiple factors viz. amyloid plaque formation, neurofibrillary tangles and inflammation. Herein we report of a new series of quinoxaline-bisthiazoles as multitarget-directed ligands (MTDLs) targeting BACE-1 and inflammation concurrently. Virtual screening of a library of novel quinoxaline-bisthiazoles was performed by docking studies. The most active molecules from the docking library were taken up for synthesis and characterized by spectral data. Compounds 8a-8n showed BACE-1 inhibition in micro molar range. One of the compounds, 8n showed BACE-1 inhibition at IC50 of 3 ± 0.07 μM. Rat paw edema inhibition in acute and chronic models of inflammation were obtained at 69 ± 0.45% and 55 ± 0.7%, respectively. Compound 8n also showed noteworthy results in AlCl3 induced AD model. The treated rats exhibited excellent antiamnesic, antiamyloid, antioxidant, and neuroprotective properties. Behavioural parameters suggested improved cognitive functions which further validates the testimony of present study. Moreover, compound 8n was found to have inherent gastrointestinal safety. This new string of quinoxaline-bisthiazoles were identified as effective lead for the generation of potent MTDLs and compound 8n was found to showcase qualities to tackle AD pathogenesis.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1173243-36-1