1173279-68-9Relevant articles and documents
Synthesis and resolution of diethyl (1S,2S)-1-amino-2-vinylcyclopropane-1-phosphonate for HCV NS3 protease inhibitors
Pyun, Hyung-Jung,Chaudhary, Kleem,Somoza, John R.,Sheng, X. Christopher,Kim, Choung U.
, p. 3833 - 3835 (2009)
We herein describe an efficient synthesis of optically active diethyl 1-amino-2-vinylcyclopropane-1-phosphonate (analogous to 1-amino-2-vinylcyclopropane-1-carboxylate). The racemic phosphonate diethyl ester was obtained from an imine derived from aminome