1173282-83-1Relevant articles and documents
One-pot synthesis of 3-[(N-alkylanilino)(aryl)methyl]indoles via a transition metal assisted three-component condensation at room temperature
Brahmachari, Goutam,Das, Suvankar
, p. E140-E145 (2014)
A simple and highly efficient protocol for the one-pot synthesis of a series of 3-[(N-alkylanilino)(aryl)methyl]indoles has been developed based on low-cost and environmentally benign zirconium oxychloride octahydrate and copper chloride dihydrate catalysts via three-component condensation between indoles, aromatic aldehydes, and N-alkylanilines at room temperature under neat condition. Mild reaction conditions, operational simplicity, high atom-economy, good yields in relatively shorter reaction times, use of low-cost and eco-friendly catalysts are some of the salient features of this protocol. A simple and highly efficient protocol for the one-pot synthesis of a series of 3-[(N-alkylanilino)(aryl)methyl]indoles has been developed based on low-cost and environmentally benign zirconium oxychloride octahydrate and copper chloride dihydrate catalysts via three-component condensation between indoles, aromatic aldehydes, and N-alkylanilines at room temperature under neat condition. Mild reaction conditions, operational simplicity, high atom-economy, good yields in relatively shorter reaction times, and use of low-cost and eco-friendly catalysts are the key advantages of the present protocol.
Iron mediated one pot three component synthesis of 3-substituted indoles via aerobic iminium ion formation
Singh, Vinay K.,Sharma, Laxmi Kant,Singh, Rana Krishna Pal
supporting information, p. 407 - 410 (2016/01/12)
An efficient and economical method was developed for the synthesis of 3 substituted indoles by a highly efficient one-pot three component coupling reaction of substituted or unsubstituted benzyl alcohol, N-methyl aniline or pyrrolidine, and indoles or sub
PANI-HBF4: A reusable polymer-based solid acid catalyst for three-component, one-pot synthesis of 3-substituted amino methyl indoles under solvent-free conditions
Devi, Chebrolu Lavanya,Rao, Vaidya Jayathirtha,Palaniappan, Srinivasan
experimental part, p. 1593 - 1603 (2012/05/04)
A simple, fast, efficient, high-yielding, and green process is developed for one-pot, three-component synthesis of 3-substituted amino methyl indoles under solvent-free conditions using polyaniline salt as polymer-based reusable solid acid catalyst at room temperature. The advantages of polyaniline salt catalyst are ease of synthesis and handling, low cost, versatality, and recyclability. Copyright Taylor & Francis Group, LLC.
Zwitterionic-type molten salt: A mild and efficient organocatalyst for the synthesis of 3-aminoalkylated indoles via three-component coupling reaction
Kundu, Dhiman,Bagdi, Avik Kr.,Majee, Adinath,Hajra, Alakananda
scheme or table, p. 1165 - 1167 (2011/06/24)
A general and efficient method has been developed for the synthesis of 3-aminoalkylated indoles by a three-component coupling of indoles, aldehydes, and amines in the presence of a catalytic amount of zwitterionic-type molten salt under solvent-free condi
One-pot three-component coupling reaction: solvent-free synthesis of novel 3-substituted indoles catalyzed by PMA-SiO2
Srihari,Singh, Vinay K.,Bhunia, Dinesh C.,Yadav
experimental part, p. 3763 - 3766 (2009/10/11)
Solvent-free PMA-SiO2-catalyzed synthesis of 3-substituted indole derivatives by a one-pot three-component coupling reaction between aldehyde, N-methyl aniline and indole is described.