1173299-13-2Relevant academic research and scientific papers
Chiral cobalt-catalyzed enantiomer-differentiating oxidation of racemic benzoins by using molecular oxygen as stoichiometric oxidant
Alamsetti, Santosh Kumar,Muthupandi, Pandi,Sekar, Govindasamy
, p. 5424 - 5427 (2009)
A study was conducted to demonstrate chiral cobalt-catalyzed enantiomer-differentiating oxidation of racemic benzoins using molecular oxygen as stoichiometric oxidant. The cobalt-catalyzed asymmetric oxidation was performed with racemic benzoins due to th
N-Heterocyclic Carbene-Catalyzed Asymmetric Benzoin Reaction in Water
Yan, Jun,Sun, Rong,Shi, Kuangxi,Li, Kai,Yang, Limin,Zhong, Guofu
, p. 7547 - 7552 (2018/06/22)
A chiral N-heterocyclic carbene-catalyzed benzoin condensation reaction in water has been developed, affording α-hydroxy ketones in good to high yields and high enantioselectivities. Water was proposed as a proton shuttle in the aqueous asymmetric condens
Solvent-Free Benzoin and Stetter Reactions with a Small Amount of NHC Catalyst in the Liquid or Semisolid State
Ema, Tadashi,Nanjo, Yoshiko,Shiratori, Sho,Terao, Yuta,Kimura, Ryo
supporting information, p. 5764 - 5767 (2016/11/17)
The intermolecular or intramolecular asymmetric benzoin reaction was catalyzed by a small amount of N-heterocyclic carbene (NHC) (0.2-1 mol %) under solvent-free conditions. The solvent-free intramolecular asymmetric Stetter reaction also proceeded efficiently with NHC (0.2-1 mol %). In some cases, even solid-to-solid or solid-to-liquid conversions took place with low catalyst loading (0.2-1 mol %).
Chiral Frustrated Lewis Pairs Catalyzed Highly Enantioselective Hydrosilylations of 1,2-Dicarbonyl Compounds
Ren, Xiaoyu,Du, Haifeng
, p. 810 - 813 (2016/02/09)
A highly enantioselective hydrosilylation of 1,2-dicarbonyl compounds was successfully realized for the first time utilizing the combination of tricyclohexylphosphine and chiral alkenylborane derived in situ from diyne as a frustrated Lewis pair catalyst. A variety of optically active α-hydroxy ketones and esters were obtained in 52-98% yields with 86-99% ee's.
Chiral Zn-catalyzed aerobic oxidative kinetic resolution of α-hydroxy ketones
Muthupandi, Pandi,Sekar, Govindasamy
experimental part, p. 512 - 517 (2011/06/17)
The aerobic oxidative kinetic resolution of racemic α-hydroxy ketones was accomplished using a chiral Zn-quinine complex as the catalyst in the presence of molecular oxygen. The resulting optimized reaction conditions were applied to resolute different types of racemic α-hydroxy ketones and a maximum of 9.2 selectivity (s) was obtained with 88% ee for the recovered α-hydroxy ketone.
