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BNP-32 (PORCINE) is a synthetic 32-amino acid peptide derived from the precursor protein pro-B-type natriuretic peptide (proBNP). It is a potent vasorelaxant and natriuretic hormone primarily secreted by the cardiac ventricles in response to excessive stretching of the heart muscle cells. BNP-32 (porcine) exerts its effects by increasing the production of cyclic guanosine monophosphate (cGMP) in vascular smooth muscle cells, leading to vasodilation and decreased vascular tone. It also acts on the kidneys to increase sodium and water excretion, promoting diuresis and natriuresis. These combined actions make BNP-32 (porcine) a promising therapeutic agent for the treatment of heart failure and other cardiovascular conditions.

117345-87-6

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Basic information
1. Product Name: BNP-32 (PORCINE)
2. Synonyms: H-SER-PRO-LYS-THR-MET-ARG-ASP-SER-GLY-CYS-PHE-GLY-ARG-ARG-LEU-ASP-ARG-ILE-GLY-SER-LEU-SER-GLY-LEU-GLY-CYS-ASN-VAL-LEU-ARG-ARG-TYR-OH;H-SER-PRO-LYS-THR-MET-ARG-ASP-SER-GLY-CYS-PHE-GLY-ARG-ARG-LEU-ASP-ARG-ILE-GLY-SER-LEU-SER-GLY-LEU-GLY-CYS-ASN-VAL-LEU-ARG-ARG-TYR-OH (DISULFIDE BRIDGE: 10-26);BNP, PORCINE;BNP (1-32), PORCINE;BNP-32 (PORCINE);BRAIN NATRIURETIC PEPTIDE (1-32), PORCINE;BRAIN NATRIURETIC PEPTIDE-32 (PORCINE);BRAIN NATRIURETIC PEPTIDE, PORCINE
3. CAS NO:117345-87-6
4. Molecular Formula: C149H250N52O44S3
5. Molecular Weight: 3570.1
6. EINECS: N/A
7. Product Categories: peptide
8. Mol File: 117345-87-6.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: −20°C
8. Solubility: N/A
9. CAS DataBase Reference: BNP-32 (PORCINE)(CAS DataBase Reference)
10. NIST Chemistry Reference: BNP-32 (PORCINE)(117345-87-6)
11. EPA Substance Registry System: BNP-32 (PORCINE)(117345-87-6)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 117345-87-6(Hazardous Substances Data)

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117345-87-6 Usage

Uses

Used in Pharmaceutical Industry:
BNP-32 (PORCINE) is used as a therapeutic agent for the treatment of heart failure and other cardiovascular conditions due to its potent vasorelaxant and natriuretic properties. It helps in reducing the symptoms of heart failure by promoting vasodilation, decreasing vascular tone, and increasing sodium and water excretion.
Used in Cardiovascular Research:
BNP-32 (PORCINE) is used as a research tool for studying the mechanisms of vasorelaxation and natriuresis in cardiovascular conditions. It aids in understanding the role of cyclic guanosine monophosphate (cGMP) in vascular smooth muscle cells and its impact on vasodilation and decreased vascular tone.
Used in Drug Development:
BNP-32 (PORCINE) is used as a lead compound in the development of new drugs targeting heart failure and other cardiovascular conditions. Its potent vasorelaxant and natriuretic properties make it a valuable candidate for the design and synthesis of novel therapeutic agents with improved efficacy and safety profiles.
Used in Diagnostics:
BNP-32 (PORCINE) can be used as a biomarker for the diagnosis and monitoring of heart failure and other cardiovascular conditions. Its levels in the blood can provide valuable information about the severity and progression of these conditions, guiding treatment decisions and patient management.

Check Digit Verification of cas no

The CAS Registry Mumber 117345-87-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,3,4 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 117345-87:
(8*1)+(7*1)+(6*7)+(5*3)+(4*4)+(3*5)+(2*8)+(1*7)=126
126 % 10 = 6
So 117345-87-6 is a valid CAS Registry Number.

117345-87-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name	Brain Natriuretic Peptide-32 Porcine

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:117345-87-6 SDS

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