1173693-63-4Relevant academic research and scientific papers
Palladium(II)-catalyzed cyclization of unsaturated hydroperoxides for the synthesis of 1,2-dioxanes
Harris, Jason R.,Waetzig, Shelli R.,Woerpel
supporting information; experimental part, p. 3290 - 3293 (2009/12/05)
The cyclization of γ, δ-unsaturated tertiary hydroperoxides in the presence of a palladium(II) catalyst afforded 1,2-dioxanes resembling biologically active natural products. A variety of substrates were screened, and synthetic manipulations were accomplished to construct compounds with structural similarity to antimalarial targets.
