117370-20-4Relevant articles and documents
Synthesis and Radioprotective Activity of Dipeptide Cysteamine and Cystamine Derivatives
Oiry, Joel,Pue, Jean Y.,Imbach, Jean L.,Fatome, Marc,Sentenac-Roumanou, Henry
, p. 297 - 301 (2007/10/02)
Some N-(dipeptidyl)-S-acetylcysteamine and N,N'-(dipeptidyl)cystamine salt derivatives were synthesized and evaluated as canditate radioprotector agents.Toxicity and radioprotective activity as the dose reduction factor (DRF) were determined in vivo on mice and compared to N-glycyl-S-acetylcysteamine trifluoroacetate.One of the most interesting compounds of this series was N-glycylglycyl-S-acetylcysteamine trifluoroacetate (8).