1173834-47-3Relevant academic research and scientific papers
Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors
Shin, Youseung,Chen, Weiming,Habel, Jeff,Duckett, Derek,Ling, Yuan Yuan,Koenig, Marcel,He, Yuanjun,Vojkovsky, Tomas,LoGrasso, Philip,Kamenecka, Theodore M.
scheme or table, p. 3344 - 3347 (2010/03/03)
A novel series of c-jun N-terminal kinase (JNK) inhibitors were designed and developed from a high-throughput-screening hit. Through the optimization of the piperazine amide 1, several potent compounds were discovered. The X-ray crystal structure of 4g sh
