1173883-67-4

Upstream product

• 1314593-38-8 N-[(1E)-2-(benzyloxy)-3-oxo-1-phenylbut-1-enyl]-2,2,2-trifluoroacetamide 
• 1314593-39-9 2,2,2-trifluoro-N-[(1E)-2-(4-methoxybenzyloxy)-3-oxo-1-phenylbut-1-enyl]acetamide 
• 1314593-42-4 2,2,2-trifluoro-N-{(1E)-3-oxo-1-phenyl-2-[2-(trimethylsilyl)ethoxy]but-1-en-1-yl}acetamide 
• 100-47-0 benzonitrile 

Downstream Products

• 1173883-78-7 1-[4-phenyl-2-(trifluoromethyl)-1,3-oxazol-5-yl]ethanol 
• 1173883-82-3 1-[4-phenyl-2-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone oxime 
• 1173883-70-9 2-[4-phenyl-2-(trifluoromethyl)-1,3-oxazol-5-yl]but-3-en-2-ol 
• 1173883-80-1 4-phenyl-2-(trifluoromethyl)-5-vinyl-1,3-oxazole 

Relevant academic research and scientific papers

Synthesis of 5-acetyloxazoles and 1,2-diketones from β-alkoxy-β- ketoenamides and their subsequent transformations

Lithiated alkoxyallenes, nitriles, and carboxylic acids have been employed as precursors in a three-component reaction leading to highly substituted β-alkoxy-β-ketoenamides. Upon treatment with trifluoroacetic acid, these enamides could be easily cyclized

Three-component synthesis of highly functionalized 5-acetyloxazoles

A study was conducted to demonstrate three-component synthesis of highly functionalized 5-acetyloxazoles. The two-step procedure allowed a highly flexible substitution pattern at C-2 and C-4 position. The synthesis procedure also allowed the incorporation