1173986-35-0Relevant academic research and scientific papers
Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7′-oxodihydroguaiaretic acid
Yamauchi, Satoshi,Masuda, Toshiya,Sugahara, Takuya,Kawaguchi, Yuya,Ohuchi, Maya,Someya, Tatsushi,Akiyama, Jun,Tominaga, Shiori,Yamawaki, Manami,Kishida, Taro,Akiyama, Koichi,Maruyama, Masafumi
experimental part, p. 2981 - 2986 (2009/04/12)
The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7′-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity.
