1173992-00-1Relevant articles and documents
Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of β-tubulin
Hutt, Oliver E.,Inagaki, Jun,Reddy, Bollu S.,Nair, Sajiv K.,Reiff, Emily A.,Henri, John T.,Greiner, Jack F.,VanderVelde, David G.,Chiu, Ting-Lan,Amin, Elizabeth A.,Himes, Richard H.,Georg, Gunda I.
, p. 3293 - 3296 (2009)
The total synthesis of 22-(3-azidobenzoyloxy)methyl epothilone C is described as a potential photoaffinity probe to elucidate the β-tubulin binding site. A sequential Suzuki-aldol-Yamaguchi macrolactonization strategy was utilized employing a novel deriva