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3,12-Dioxo-5α-cholan-24-oic acid methyl ester is a chemical compound with the molecular formula C24H38O4. It is a derivative of the bile acid family, specifically a modified form of cholic acid. 3,12-Dioxo-5α-cholan-24-oic acid methyl ester features a cholestane skeleton with a 3,12-dioxo group, indicating the presence of two carbonyl groups at the 3 and 12 positions, and a 24-oic acid group, which is a carboxylic acid functional group at the 24th position. The methyl ester group is attached to the carboxylic acid, making it a methyl ester derivative. 3,12-Dioxo-5α-cholan-24-oic acid methyl ester is known for its potential applications in pharmaceutical research, particularly in the study of bile acid metabolism and as a precursor in the synthesis of other bile acid derivatives. It is also used as an intermediate in the preparation of various drugs and diagnostic agents.

1174-86-3

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1174-86-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1174-86-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,7 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1174-86:
(6*1)+(5*1)+(4*7)+(3*4)+(2*8)+(1*6)=73
73 % 10 = 3
So 1174-86-3 is a valid CAS Registry Number.

1174-86-3Relevant academic research and scientific papers

The Reactivity of Silyl Ethers to the Swern Reagent

Afonso, Carlos M.,Barros, M. Teresa,Maycock, Christopher D.

, p. 1221 - 1224 (2007/10/02)

The activated Me2SO reagent , 'Swern reagent'> oxidises the trimethylsilyl ethers of primary and secondary alcohols directly to the corresponding carbonyl compound.Useful selectivity is possible where competing ether groups possess large differences of steric hindrance.Dimethyl-t-butylsilyl ethers are unaffected by this reagent.

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