1174040-01-7Relevant academic research and scientific papers
One-pot concise syntheses of benzimidazo[2,1-a]isoquinolines by a microwave-accelerated tandem process
Okamoto, Noriko,Sakurai, Keisuke,Ishikura, Minoru,Takeda, Kei,Yanada, Reiko
, p. 4167 - 4169 (2009)
Direct, efficient syntheses of the benzimidazo[2,1-a]isoquinoline ring system have been achieved with 2-bromoarylaldehydes, terminal alkynes, and 1,2-phenylenediamines by a microwave-accelerated tandem process in which a Sonogashira coupling, 5-endo cyclization, oxidative aromatization, and 6-endo cyclization can be performed in a single synthetic operation.
