117406-89-0

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 117169-44-5 Methanesulfonic acid (1S,2S,3R,5S)-3-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-methanesulfonyloxymethyl-cyclopentylmethyl ester 
• 117109-81-6 (Dimethoxy-phosphoryl)-acetic acid (1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 117300-42-2 (1S,2R,3aR,6aS)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-5-methylsulfanyl-5-(toluene-4-sulfonyl)-octahydro-pentalene 
• 57707-91-2 (1S,2R,5S)-8-(+)-phenylmenthol 
• 104172-98-7 (3aS,4S,5R,6aR)-5-((tert-butyldimethylsilyl)oxy)-4-(((tert-butyldimethylsilyl)oxy)methyl)hexahydropentalen-2(1H)-one 
• 65253-04-5 (-)-8-phenylmenthol 
• 113368-89-1 (-)-8-phenylmenthyl dimethyl phosphonoacetate 
• 117109-83-8 (Dimethoxy-phosphoryl)-acetic acid (1S,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 

Downstream Products

• 57707-91-2 (1S,2R,5S)-8-(+)-phenylmenthol 
• 117300-46-6 (Z)-2-((3aS,4S,5R,6aS)-5-(((tert-butyldimethylsilyl)oxy-4-(tert-butyldimethylsilyl)oxy)methyl)hexahydropentalen-2(1H)-ylidene)ethanol 
• 117300-45-5 (E)-2-(((3aS,4S,5R,6aS)-5-((tert-butyldimethylsilyl)oxy-4-(tert-butyldimethylsilyl)oxy)methyl)hexahydropentalen-2(1H)-ylidene)ethanol 

Relevant academic research and scientific papers

SYNTHESIS OF OPTICALLY ACTIVE 3-OXA-CARBACYCLIN PRECURSORS FEATURING ASYMMETRIC HORNER-EMMONS REACTION

An enantiselective synthesis of 5 is described.Asymmetric Horner-Emmons reactions with the chiral phosphonate 6 are key steps in the synthesis of the allylic alcohols E-8 and E-11 from the ketones 5 and 9, respectively.

E- OR Z-SELECTIVE HORNER-WITTIG REACTIONS OF SUBSTITUTED BICYCLOOCTANE-3-ONES WITH CHIRAL PHOSPHONOACETATES

The Horner-Wittig reaction of substituted bicyclo(3.3.0)octane-3-ones with chiral phosphonoacetates 2 gave the corresponding unsaturated esters in E/Z-ratios of up to 91 : 9.