1174062-80-6

Basic information

• Product Name: 2-(4-bromophenyl)-N-phenylpropanamide
• Synonyms: 2-(4-bromophenyl)-N-phenylpropanamide
• CAS NO: 1174062-80-6
• Molecular Weight: 304.186
• Mol File: 1174062-80-6.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-N-phenylpropanamide(1174062-80-6)
• EPA Substance Registry System: 2-(4-bromophenyl)-N-phenylpropanamide(1174062-80-6)

Safety Data

• Hazardous Substances Data: 1174062-80-6(Hazardous Substances Data)

Upstream product

• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 201230-82-2 carbon monoxide 
• 62-53-3 aniline 
• 1174062-77-1 1-bromo-4-(1,1-dibromoprop-1-en-2-yl)benzene 

Relevant articles and documents

Asymmetric Markovnikov Hydroaminocarbonylation of Alkenes Enabled by Palladium-Monodentate Phosphoramidite Catalysis

A palladium-catalyzed asymmetric Markovnikov hydroaminocarbonylation of alkenes with anilines has been developed for the atom-economical synthesis of 2-substituted propanamides bearing an α-stereocenter. A novel phosphoramidite ligand L16 was discovered which exhibited very high reactivity and selectivity in the reaction. This asymmetric Markovnikov hydroaminocarbonylation employs readily available starting materials and tolerates a wide range of functional groups, thus providing a facile and straightforward method for the regio- and enantioselective synthesis of 2-substituted propanamides under ambient conditions. Mechanistic studies revealed that the reaction proceeds through a palladium hydride pathway.

Palladium-catalyzed amidation-hydrolysis reaction of gem-dihaloolefins: Efficient synthesis of homologated carboxamides from ketones

A simple and efficient palladium-catalyzed amidation-hydrolysis reaction has been developed to afford N-aryl monosubstituted carboxamides in good to excellent yields from easily accessible ketone-derived gem-dihaloolefins and aryl amines.