1174064-57-3

Usage

Uses

Used in the Production of Polyurethane Materials:
4-isocyanato-1-methyl-1H-pyrazole is used as a key component in the production of polyurethane foams, elastomers, and adhesives. Its reactivity allows for the creation of durable and versatile materials with a wide range of applications in various industries.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-isocyanato-1-methyl-1H-pyrazole serves as an intermediate in the synthesis of various drugs. Its ability to participate in different types of reactions makes it a valuable tool for developing new pharmaceutical compounds with specific therapeutic properties.
Used in Agrochemical Production:
4-isocyanato-1-methyl-1H-pyrazole is also employed as an intermediate in the synthesis of agrochemicals. Its reactivity and versatility contribute to the development of effective products for agricultural applications, such as pesticides and herbicides.
Used in Organic Chemistry Research:
As a highly reactive isocyanate compound, 4-isocyanato-1-methyl-1H-pyrazole is utilized in organic chemistry research to explore new reaction pathways and develop innovative materials and compounds with potential applications in various fields.

Upstream product

• 5952-92-1 1-methyl-1H-pyrazole-4-carboxylic acid 

Relevant academic research and scientific papers

ISOINDOLINONE COMPOUNDS

Disclosed herein is a compound or pharmaceutically acceptable salts or stereoisomers thereof of of formula I wherein X1 is linear or branched C1-6 alkyl, C3-6 cycloalkyl, -C1-6 alkyl C3-6 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, C1-6 alkyl C6-10 aryl, C1-6 alkyl 5-10 membered heteroaryl, wherein X1 is unsubstituted or substituted with one or more of halogen, linear or branched C1-6 alkyl, linear or branched C1-6 heteroalkyl, CF3, CHF2, -O-CHF2, -O-(CH2)2-OMe, OCF3, C1-6 alkylamino, -CN, -N(H)C(O)-C1- 6alkyl, -OC(O)-C1-6alkyl, -OC(O)-C1-4alkylamino, -C(O)O-C1-6alkyl, -COOH, - CHO, -C1-6alkylC(O)OH, -C1-6alkylC(O)O-C1-6alkyl, NH2, C1-6 alkoxy or C1-6 alkylhydroxy; X2 is hydrogen, C6-10 aryl, 5-10 membered heteroaryl, -O-(5-10 membered heteroaryl), 4-8 membered heterocycloalkyl, C1-4 alkyl 4-8 membered heterocycloalkyl, -O-(4-8 membered heterocycloalkyl), -O-C1-4 alkyl-(4-8 membered heterocycloalkyl), -OC(O)-C1-4alkyl-4-8 membered heterocycloalkyl or C6 aryloxy, wherein X2 is unsubstituted or substituted with one or more of linear or branched C1-6 alkyl, NH2, NMe2 or 5-6 membered heterocycloalkyl; n is 0, 1 or 2.

AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE

The present invention relates to anhydrous and hydrated forms of Compound 1, which qre useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.

AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITORS OF C-MET PROTEIN KINASE

The present invention relates to compounds of formula (I), which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula (I) and methods of using the compositions in the treatment of proliferative disorders