1174064-57-3

Basic information

• Product Name: 4-isocyanato-1-methyl-1H-pyrazole
• Synonyms: 4-isocyanato-1-methyl-1H-pyrazole
• CAS NO: 1174064-57-3
• Molecular Formula: C₅H₅N₃O
• Molecular Weight: 123.1127
• Mol File: 1174064-57-3.mol
• Article Data: 3

Chemical Properties

• Appearance: Yellow/Liquid, May Contain Fine Suspension
• CAS DataBase Reference: 4-isocyanato-1-methyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-isocyanato-1-methyl-1H-pyrazole(1174064-57-3)
• EPA Substance Registry System: 4-isocyanato-1-methyl-1H-pyrazole(1174064-57-3)

Safety Data

• Hazardous Substances Data: 1174064-57-3(Hazardous Substances Data)

Usage

General Description

4-isocyanato-1-methyl-1H-pyrazole is a chemical compound with the molecular formula C5H5N3O. It is a highly reactive isocyanate compound that is used in the production of polyurethane foams, elastomers, and adhesives. It is also employed as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-isocyanato-1-methyl-1H-pyrazole is a versatile building block in organic chemistry and is known for its ability to readily participate in various types of reactions, making it a valuable tool for the development of new materials and compounds. It is important to handle this chemical with caution due to its reactivity and potential health hazards.

Upstream product

• 5952-92-1 1-methyl-1H-pyrazole-4-carboxylic acid 

Relevant articles and documents

ISOINDOLINONE COMPOUNDS

Disclosed herein is a compound or pharmaceutically acceptable salts or stereoisomers thereof of of formula I wherein X1 is linear or branched C1-6 alkyl, C3-6 cycloalkyl, -C1-6 alkyl C3-6 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, C1-6 alkyl C6-10 aryl, C1-6 alkyl 5-10 membered heteroaryl, wherein X1 is unsubstituted or substituted with one or more of halogen, linear or branched C1-6 alkyl, linear or branched C1-6 heteroalkyl, CF3, CHF2, -O-CHF2, -O-(CH2)2-OMe, OCF3, C1-6 alkylamino, -CN, -N(H)C(O)-C1- 6alkyl, -OC(O)-C1-6alkyl, -OC(O)-C1-4alkylamino, -C(O)O-C1-6alkyl, -COOH, - CHO, -C1-6alkylC(O)OH, -C1-6alkylC(O)O-C1-6alkyl, NH2, C1-6 alkoxy or C1-6 alkylhydroxy; X2 is hydrogen, C6-10 aryl, 5-10 membered heteroaryl, -O-(5-10 membered heteroaryl), 4-8 membered heterocycloalkyl, C1-4 alkyl 4-8 membered heterocycloalkyl, -O-(4-8 membered heterocycloalkyl), -O-C1-4 alkyl-(4-8 membered heterocycloalkyl), -OC(O)-C1-4alkyl-4-8 membered heterocycloalkyl or C6 aryloxy, wherein X2 is unsubstituted or substituted with one or more of linear or branched C1-6 alkyl, NH2, NMe2 or 5-6 membered heterocycloalkyl; n is 0, 1 or 2.

AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITORS OF C-MET PROTEIN KINASE

The present invention relates to compounds of formula (I), which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula (I) and methods of using the compositions in the treatment of proliferative disorders