1174139-16-2Relevant articles and documents
On the emerging role of chemistry in the fashioning of biologics: Synthesis of a bidomainal fucosyl GM1-based vaccine for the treatment of small cell lung cancer
Nagorny, Pavel,Woo, Han Kim,Wan, Qian,Lee, Dongjoo,Danishefsky, Samuel J.
experimental part, p. 5157 - 5162 (2009/12/08)
(Chemical Equation Presented) The synthesis of the novel small cell lung cancer (SCLC) fucosyl GM1-based vaccine construct, featuring insertion of the HLA-DR binding 15 amino acid sequence derived from Plasmodium falciparum, is described. The resultant gl