117416-55-4Relevant academic research and scientific papers
Diastereoselective intramolecular Friedel-Crafts alkylation of tetralins
Liebert, Clemence,Brinks, Marion K.,Capacci, Andrew G.,Fleming, Matthew J.,Lautens, Mark
, p. 3000 - 3003 (2011/08/05)
An efficient and versatile synthesis of cis-hexahydrobenzophenanthridines starting from readily available tetralins has been developed using an intramolecular Friedel-Crafts alkylation as a key step. The substrates were prepared via a highly stereocontrolled rhodium-catalyzed ring-opening reaction of meso-oxabicyclic alkenes and a hydrogenation sequence. Thus, a wide variety of complex tetracyclic compounds have been isolated with a high level of regio-, diastereo-, and enantioselectivity.
A GENERAL METHOD FOR STEREO- AND REGIO-SPECIFIC OXYAMINATION OF OLEFINS
Das, Jagabandhu
, p. 907 - 916 (2007/10/02)
A new synthetic method for stereo and regioscpecific oxyamination of olefins is described.
