SCR-1481B1 is a chemical compound that has been studied for its potential use in the fields of oncology and neurology. It is a brain-penetrant inhibitor of cyclin-dependent kinase 7 (CDK7), a key regulator protein in cell division. Research has shown SCR-1481B1 has significant antitumor effects, particularly in the treatment of glioblastoma and neuroblastoma. It achieves this by disrupting the transcription process, resulting in the reduction of oncotes, inactivation of tumor cells, and suppression of cancer growth. Its potential makes it a subject of interest in the development of targeted therapeutic drugs for cancer treatment.
1174161-86-4
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Basic information
- Product Name: SCR-1481B1
- Synonyms: c-Met inhibitor 2;SCR-1481B1;QPFPEXKJGICONN-UHFFFAOYSA-N
- CAS NO:1174161-86-4
- Molecular Formula: C28H29ClF2N5O10P
- Molecular Weight: 699.99
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: SCR-1481B1(CAS DataBase Reference)
- NIST Chemistry Reference: SCR-1481B1(1174161-86-4)
- EPA Substance Registry System: SCR-1481B1(1174161-86-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1174161-86-4(Hazardous Substances Data)
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1174161-86-4 Usage
Uses
Used in Oncology:SCR-1481B1 is used as an antitumor agent for its significant effects in treating glioblastoma and neuroblastoma. It functions by inhibiting CDK7, disrupting the transcription process, and leading to the reduction of oncotes, inactivation of tumor cells, and suppression of cancer growth.
Used in Neurology:
SCR-1481B1 is used as a potential therapeutic agent for neurological conditions, given its ability to penetrate the brain and target CDK7, which plays a role in cell division and may be implicated in certain neurological disorders.
Further research and clinical trials are necessary to fully understand the safety, effectiveness, and therapeutic viability of SCR-1481B1 in these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1174161-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,4,1,6 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.Calculate Digit Verification of CAS Registry Number 1174161-86:
(9*1)+(8*1)+(7*7)+(6*4)+(5*1)+(4*6)+(3*1)+(2*8)+(1*6)=144
144 % 10 = 4
So 1174161-86-4 is a valid CAS Registry Number.
1174161-86-4Upstream product
1174161-86-4Downstream Products
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SCR-1481B1
