1174231-58-3Relevant academic research and scientific papers
Improved air-stable solid aromatic and heterocyclic zinc reagents by highly selective metalations for negishi cross-couplings
Stathakis, Christos I.,Bernhardt, Sebastian,Quint, Valentin,Knochel, Paul
, p. 9428 - 9432 (2012/10/29)
Directed metalation using TMPMgCl·LiCl (TMP=2,2,6,6- tetramethylpiperidide) and subsequent transmetalation with Zn(OPiv)2 leads to aryl and heteroaryl zinc pivalates. After solvent evaporation, easy-to-handle fine powders are obtained that reta
Synthesis of fully substituted pyrazoles via regio- and chemoselective metalations
Despotopoulou, Christina,Klier, Lydia,Knochel, Paul
supporting information; experimental part, p. 3326 - 3329 (2009/12/01)
The full functionalization of the pyrazole ring was achieved by successive regioselective metalations using TMPMgCI-LiCI and TMP2Mg.2LiCI. Trapping with various electrophiles led to trisubstituted pyrazoles. An application to the synthesis of the acaricide Tebufenpyrad is reported.
