1174304-73-4 Usage
General Description
[4-(1H-PYRAZOL-5-YL)PHENYL]BORONIC ACID is a chemical compound that belongs to the class of boronic acids. It is a white to off-white powder that is used in various organic synthesis reactions. [4-(1H-PYRAZOL-5-YL)PHENYL]BORONIC ACID is often employed as a reagent in the formation of carbon-carbon bonds through Suzuki coupling reactions. It also has potential applications in the pharmaceutical industry, particularly in the development of new drugs and drug delivery systems. Additionally, [4-(1H-PYRAZOL-5-YL)PHENYL]BORONIC ACID has shown promise in the field of materials science, where it can be used in the preparation of functionalized materials and as a building block for the synthesis of complex organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1174304-73-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,4,3,0 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1174304-73:
(9*1)+(8*1)+(7*7)+(6*4)+(5*3)+(4*0)+(3*4)+(2*7)+(1*3)=134
134 % 10 = 4
So 1174304-73-4 is a valid CAS Registry Number.
1174304-73-4Relevant articles and documents
Scope of the palladium-catalyzed aryl borylation utilizing bis-boronic acid
Molander, Gary A.,Trice, Sarah L. J.,Kennedy, Steven M.,Dreher, Spencer D.,Tudge, Matthew T.
supporting information; experimental part, p. 11667 - 11673 (2012/09/05)
The Suzuki-Miyaura reaction has become one of the more useful tools for synthetic organic chemists. Until recently, there did not exist a direct way to make the most important component in the coupling reaction, namely the boronic acid. Current methods to make boronic acids often employ harsh or wasteful reagents to prepare boronic acid derivatives and require additional steps to afford the desired boronic acid. The scope of the previously reported palladium-catalyzed, direct boronic acid synthesis is unveiled, which includes a wide array of synthetically useful aryl electrophiles. It makes use of the newly available second generation Buchwald XPhos preformed palladium catalyst and bis-boronic acid. For ease of isolation and to preserve the often sensitive C-B bond, all boronic acids were readily converted to their more stable trifluoroborate counterparts.
