1174412-33-9Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents
Matsuya, Yuji,Kobayashi, Yuta,Kawaguchi, Takanori,Hori, Ayana,Watanabe, Yuka,Ishihara, Kentaro,Ahmed, Kanwal,Wei, Zheng-Li,Yu, Da-Yong,Zhao, Qing-Li,Kondo, Takashi,Nemoto, Hideo
experimental part, p. 5799 - 5813 (2010/03/03)
Various artificial macrosphelides were designed and synthesized, including ring-enlarged analogues and epothilone-hybrid compounds. Syntheses were accomplished in an efficient manner by using a ring-closing metathesis (RCM) strategy in a key macro-cycliza
