1174427-74-7Relevant academic research and scientific papers
Selective aerobic oxidative dibromination of alkenes with aqueous HBr and sodium nitrite as a catalyst
Podgorsek, Ajda,Eissen, Marco,Fleckenstein, Jens,Stavber, Stojan,Zupan, Marko,Iskra, Jernej
experimental part, p. 120 - 126 (2010/04/22)
Various alkenes (internal, terminal, aryl and alkyl substituted) and 1,2-diphenylethyne were efficiently and selectively dibrominated using 2 equivalents of 48% aqueous hydrobromic acid, with air as an oxidant and sodium nitrite as a catalyst. Despite the presence of water, only trans dibromination occurred producing anti-1,2-dibromoalkanes and (E)-1,2-dibromo-1,2- diphenylethene. A comparison of resource demand, waste production and environmental, health and safety issues of the NaNO2 catalyzed aerobic bromination with molecular bromine and other oxidative bromination methods revealed that the proposed method is not only selective and effective but has a better environmental profile.
