117449-75-9

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-2-hydroxy-6-methylpyridine-3-carboxylic acid is used as a building block or intermediate in the synthesis of various pharmaceutical compounds. Its structural features and reactivity make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
5-Chloro-2-hydroxy-6-methylpyridine-3-carboxylic acid is used as a key intermediate in the production of agrochemicals, such as pesticides and herbicides. Its unique chemical properties can contribute to the development of novel and effective agrochemicals with improved performance and selectivity.
Further Research and Studies:
5-Chloro-2-hydroxy-6-methylpyridine-3-carboxylic acid warrants further research and studies to explore its biological activities and synthetic applications. Understanding its potential uses and optimizing its synthesis and properties can lead to the development of innovative products and applications in various industries.

Upstream product

• 38116-61-9 2-hydroxy-6-methylnicotinic acid 

Downstream Products

• 934361-39-4 methyl 5-chloro-2-hydroxy-6-methylpyridine-3-carboxylate 

Relevant academic research and scientific papers

ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS

Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.

Benzo- and pyrido-1,4-oxazepin-5-ones and -thiones: Synthesis and structure-activity relationships of a new series of H1 antihistamines

A series of novel benzo- and pyrido-1,4-oxazepinones and -thiones which represents a new structural class of compounds possessing H1 antihistaminic acitivy was synthesized, and the SARs were evaluated. The antihistamine activity was determined by blockade of histamine-induced lethality in guinea pigs. The sedative potential was determined by comparison of the EEG profiles of the compounds with those of known sedating and nonsedating antihistamines. Several of the compounds were shown to possess potent H1 antihistaminic activity and to be free of the cortical slowing with synchronized waves and spindling activity found in the EEG of sedative antihistamines. One compound, 2-[2-(dimethylamino)ethyl]-3,4-dihydro-4-methylpyrido[3,2-f]-1,4-oxazeN pine-5(2H)-thione (rocastine) is currently undergoing clinical evaluation as a nonsedating H1 antihistamine.

Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof

Aromatic azepinones and thiones having the formula STR1 wherein; A is benzene, naphthalene, quinoline or pyridine; B is oxygen or sulfur; E is oxygen, sulfur or STR2 n is 1, 2 or 3; Z is an amino or a heterocyclic nitrogen-containing radical; R is hydrogen, loweralkyl, cycloalkyl or phenylloweralkyl; Y is halo, loweralkyl, loweralkoxy, diloweralkylamino, nitro, amino, loweracetylamino, trifluoromethyl, phenyl or phenyl substituted by one to three Y' radicals selected from halo, loweralkyl, loweralkoxy, diloweralkylamino, nitro, amino, loweracylamino or trifluoromethyl; and having antihistaminic utility, a process for the preparation thereof and chemical intermediates therefor are disclosed.