1174514-22-7Relevant academic research and scientific papers
Diastereo- and enantioselective Aza-MBH-type reaction of nitroalkenes to N-tosylimines catalyzed by bifunctional organocatalysts
Wang, Xiao,Chen, Yong-Fei,Niu, Liang-Feng,Xu, Peng-Fei
supporting information; scheme or table, p. 3310 - 3313 (2009/12/05)
The first example of diastereo- and enantioselective aza-MBH-type reaction was accomplished by the asymmetric synthesis of β-nitro-γenamines via a (1R,2R)-diaminocyclohexane thiourea derivative mediated tandem Michael addition and aza-Henry reaction in good yields (up to 95%) and high enantioselectivities (up to 91% ee) and diastereoselectivities (up to 1:99 dr).
