1174549-41-7Relevant academic research and scientific papers
Efficient synthesis of bongkrekic acid. Three-component convergent strategy
Sato, Yukiko,Aso, Yoshifumi,Shindo, Mitsuru
scheme or table, p. 4164 - 4166 (2009/12/01)
An efficient total synthesis of the apoptosis inhibitor bongkrekic acid was accomplished using a three-component convergent strategy involving a Kocienski-Julia olefination and a Suzuki-Miyaura coupling, in which the longest linear sequence was 18 steps and proceeded in 6.4% overall yield. The torquoselective olefination also contributed to the shortening of the synthesis.
