1174574-34-5Relevant academic research and scientific papers
An expeditious synthesis of cyanohydrin trimethylsilyl ethers using tetraethylammonium 2-(carbamoyl)benzoate as a bifunctional organocatalyst
Dekamin, Mohammad G.,Sagheb-Asl, Solmaz,Reza Naimi-Jamal
, p. 4063 - 4066 (2009)
Phthalimide and tetraethylammonium hydroxide react via an unusual pathway to afford tetraethylammonium 2-(carbamoyl)benzoate (TEACB) which is of interest as a bifunctional organocatalyst. TEACB (0.5 mol %) was found to catalyze the addition of trimethylsi
Tetraethylammonium 2-(carbamoyl)benzoate as a bifunctional organocatalyst for one-pot synthesis of Hantzsch 1,4-dihydropyridine and polyhydroquinoline derivatives
Yarhosseini, Mahsa,Javanshir, Shahrzad,Dekamin, Mohammad G.,Farhadnia, Mohammad
, p. 1779 - 1787 (2016/09/28)
Abstract: A green, convenient, and environment-friendly approach for the synthesis of biologically active Hantzsch 1,4-dihydropyridine and polyhydroquinoline derivatives in the presence of tetraethylammonium 2-(carbamoyl)benzoate, as an effective bifunctional metal-free catalyst, has been developed via a one-pot multicomponent reaction of various aldehydes, ethyl acetoacetate or cyclic 1,3-dicarbonyl compounds, and ammonium acetate in EtOH under reflux conditions. The proposed methodology is capable of providing the desired products in good to excellent yields and short reaction time with straightforward work-up and a low-cost procedure. Graphical abstract: [Figure not available: see fulltext.]
