1174582-36-5Relevant academic research and scientific papers
Synthesis of N-(substituted benzyl)-2-(3′,5′-dimethyl-4′- hydroxyphenyl) acetamides
China Raju
experimental part, p. 1903 - 1905 (2009/05/27)
4-Benzyloxy-3,5-dimethylphenylacelate 1 reacts with substituted benzyl amines 2a-e affords N-substituted benzyl-2-(4′-benzyloxy-3′, 5′-dimethylphenyl) acetamides 3a-e, which on debenzylation give N-substituted benzyl-2-(3′,5′-dimethyl-4′-hydroxy phenyl) acetamides 4a-e in very good yields which are important intermediates for the synthesis of 1,2,3,4-tetrahydroisoquinolines.
