1174638-99-3Relevant academic research and scientific papers
Synthesis of glycosyl fluorides from (phenylthio)glycosides using IF5-pyridine-HF
Kunigami, Masataka,Hara, Shoji
, p. 78 - 80 (2015)
IF5-pyridine-HF, an air- and moisture-stable fluorinating reagent, was applied to the synthesis of glycosyl fluorides from (phenylthio)glycosides. Common protecting groups of alcohol and diol can tolerate the reaction conditions performed, and therefore, the present method is applicable to the synthesis of various glycosyl fluorides.
FLUORINATING AGENT
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Paragraph 0092; 0104, (2016/12/01)
An object of the present invention is to provide a novel substance that has a high reactivity as a fluorinating agent, is effectively used in various fluorination reactions, and is safely handled even in air. As the solution for achieving this object, the present invention provides a complex obtained by reacting bromine trifluoride with at least one metal halide selected from the group consisting of halogenated metals and halogenated hydrogen metals in a nonpolar solvent. This complex serves as a fluorinating agent that provides excellent fluorination performance and that is stable in air.
Direct C-glycosylation of organotrifluoroborates with glycosyl fluorides and its application to the total synthesis of (+)-varitriol
Zeng, Jing,Vedachalam, Seenuvasan,Xiang, Shaohua,Liu, Xue-Wei
supporting information; experimental part, p. 42 - 45 (2011/03/22)
A mild, stereoselective, and quick approach to accessing alkynyl and alkenyl C-glycosides via BF3?Et2O promoted coupling of organotrifluoroborates and glycosyl fluorides is reported. The application of this method was further demonstrated by the concise and efficient total synthesis of (+)-varitriol in only seven steps.
Reactions of trimethylsilyl fluorosulfonyldifluoroacetate with purine and pyrimidine nucleosides
Rapp, Magdalena,Cai, Xiaohong,Xu, Wei,Dolbier Jr., William R.,Wnuk, Stanislaw F.
experimental part, p. 321 - 328 (2009/12/04)
Difluorocarbene, generated from trimethylsilyl fluorosulfonyldifluoroacetate (TFDA), reacts with the uridine and adenosine substrates preferentially at the enolizable amide moiety of the uracil ring and the 6-amino group of the purine ring. 2′,3′-Di-O-ben
