117468-08-3Relevant articles and documents
Molybdenum-MCM-41 silica as heterogeneous catalyst for olefin epoxidation
Bigi, Franca,Piscopo, Calogero Giancarlo,Predieri, Giovanni,Sartori, Giovanni,Scotti, Roberto,Zanoni, Robertino,Maggi, Raimondo
, p. 108 - 113 (2014)
MCM-41-supported molybdenum/bis-dithiocarbamate complex can be efficiently utilized, after treatment with tert-butylhydroperoxide (TBHP), for the epoxidation of alkenes under solventless conditions. The treatment with TBHP allows the formation of the real catalyst through oxidative decomposition of the complex affording well dispersed Mo(VI) species grafted onto the silica surface through the silanol groups. Experimental results, catalytic efficiency and spectroscopy data, allow to advance some hypotheses on the molybdenum-grafted catalyst formation. The grafted catalyst can be reused several times in the model epoxidation of cyclohexene affording the epoxide with very good yield; only during the first run a modest molybdenum leaching is observed. Both cyclic and linear alkenes can be epoxidized in good to excellent yields and selectivities.
Design and synthesis of violet odorants with bicyclo[6.4.0]dodecene and bicyclo[5.4.0]undecene skeletons
Kraft, Philip
, p. 695 - 703 (1999)
The Diels-Alder reaction of 1,2-bis(methylene)cyclooctane (13), 4- methylenespiro[2.7]decane (29), 4-methylenespiro[2.6]nonane (40) and 4- methylenespiro[2.7]dec-8-ene (46) with different α,β-unsaturated carbonyl compounds afforded various derivatives 16, 18, 20, 22, 24, 26, 32, 36, 38, 41, 42 and 47 of a molecular-modeled lead compound 9. These less flexible β- ionone-mimics with bicyclo[6.4.0]dodecene and bicyclo[5.4.0]undecene skeletons possess interesting fruity-woody-floral odor notes and provide insight into the structure-odor correlation of violet odorants. 5-(2- Methylcycloalk-1-en-1-yl)hex-3-en-2-ones (e.g. 35) were identified as byproducts of the Rh(I)-catalyzed reactions of the vinylcyclopropanes 29 and 40.
Co(ii) complexes loaded into metal-organic frameworks as efficient heterogeneous catalysts for aerobic epoxidation of olefins
Wang, Jingjing,Yang, Mu,Dong, Wenjun,Jin, Zhaokui,Tang, Jia,Fan, Shuang,Lu, Yunfeng,Wang, Ge
, p. 161 - 168 (2016)
A series of efficient cobalt(ii)-anchored Cr-MOF (Cr-MIL-101-NH2) catalysts, such as Co(ii)@Cr-MIL-101-Sal, Co(ii)@Cr-MIL-101-P2I and Co(ii)@Cr-MIL-101-P3I, have been successfully synthesized by one-pot modification of the terminal amino group with salicylaldehyde, pyridine-2-aldehyde or pyridine-3-aldehyde and anchoring of Co(ii) ions into the mesoporous Cr-MOF supports. The Co(ii)@Cr-MIL-101-P2I catalyst exhibited high catalytic performance for epoxidation of olefins with air as an oxidant due to the nitrogen atom in the pyridine ring as a strong electron-withdrawing substituent, high dispersion of Co(ii) species and high surface area for sufficient contact between the substrate and active sites. The strong coordination interaction between the Co(ii) ions and chelating groups in the Co(ii)@Cr-MIL-101-P2I catalyst guaranteed the excellent recycling performance. Furthermore, the synthesized Co(ii)@Cr-MIL-101-P2I catalyst realized its general applicability towards various olefins, such as cyclic olefins, tri-substituted olefins, aliphatic olefins and aromatic olefins.
Chemoselective epoxidation of dienes using polymer-supported manganese porphyrin catalysts
Brulé, Emile,De Miguel, Yolanda R.,Hii, King Kuok
, p. 5913 - 5918 (2004)
Manganese porphyrin catalysts supported on different polymer resins were assessed in the selective epoxidation of three dienes. The recyclability of the catalysts was examined.
MONOACYLGLYCEROL LIPASE MODULATORS
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Page/Page column 75; 84, (2021/10/02)
Fused and bridged compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: (I) wherein R1a, R1b, R2, and R3, are defined herein.
A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates
Baalmann, Mathis,Bitsch, Sebastian,Deweid, Lukas,Ilkenhans, Nadja,Kolmar, Harald,Neises, Laura,Schneider, Hendrik,Werther, Philipp,Wilhelm, Jonas,Wolfring, Martin,Wombacher, Richard,Ziegler, Michael J.
supporting information, p. 12885 - 12893 (2020/06/02)
Bioorthogonal chemistry holds great potential to generate difficult-to-access protein–protein conjugate architectures. Current applications are hampered by challenging protein expression systems, slow conjugation chemistry, use of undesirable catalysts, or often do not result in quantitative product formation. Here we present a highly efficient technology for protein functionalization with commonly used bioorthogonal motifs for Diels–Alder cycloaddition with inverse electron demand (DAinv). With the aim of precisely generating branched protein chimeras, we systematically assessed the reactivity, stability and side product formation of various bioorthogonal chemistries directly at the protein level. We demonstrate the efficiency and versatility of our conjugation platform using different functional proteins and the therapeutic antibody trastuzumab. This technology enables fast and routine access to tailored and hitherto inaccessible protein chimeras useful for a variety of scientific disciplines. We expect our work to substantially enhance antibody applications such as immunodetection and protein toxin-based targeted cancer therapies.
Synthesis of functionalized carbon microspheres and their catalyst activity in C—O and C—N bond formation reactions
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Page/Page column 9, (2019/02/14)
Disclosed herein is a simple process for functionalization/grafting of carbon microspheres obtained from bagasse with various active functional groups onto it and use of the same as catalyst for various organic reactions, having very high selectivity and conversion rate.
