1174749-47-3Relevant academic research and scientific papers
New chiral N-heterocyclic carbene ligands in palladium-catalyzed α-arylations of amides: Conformational locking through allylic strain as a device for stereocontrol
Jia, Yi-Xia,Katayev, Dmitry,Bernardinelli, Gerald,Seidel, Thomas M.,Kuendig, E. Peter
supporting information; experimental part, p. 6300 - 6309 (2010/07/14)
New Enders/Herrmann-type chiral N-heterocyclic carbene (NHC) ligands have been developed and applied in asymmetric palladium-catalyzed intramolecular α-arylations of amides. The best ligands feature the bulky tert-butyl group and ortho-substituted aryl gr
Palladium-catalyzed enantioselective α-arylation and α-vinylation of oxindoles facilitated by an axially chiral p-stereogenic ligand
Taylor, Alexander M.,Altman, Ryan A.,Buchwald, Stephen L.
supporting information; experimental part, p. 9900 - 9901 (2009/12/06)
(Chemical Equation Presented) The enantioselective α-arylation and α-vinylation of oxindoles catalyzed by Pd and a biarylmonophosphine ligand with both axial and phosphorus-based chirogenicity is reported. The resultant quaternary carbon stereocenters are
