1174755-84-0Relevant articles and documents
Stereoselective Synthesis of Aryl Cyclopentene Scaffolds by Heck-Matsuda Desymmetrization of 3-Cyclopentenol
Angnes, Ricardo A.,Oliveira, Juliana M.,Oliveira, Caio C.,Martins, Nelson C.,Correia, Carlos Roque D.
supporting information, p. 13117 - 13121 (2015/10/20)
A new enantioselective Heck-Matsuda desymmetrization reaction was accomplished by using 3-cyclopentenol to produce chiral five-membered 4-aryl cyclopentenol scaffolds in good yields and high ee's, together with some 3-aryl-cyclopentanones as minor products. Mechanistically, the hydroxyl group of 3-cyclopentenol acts as a directing group and is responsible for the cisarrangement in the formation of the 4-aryl-cyclopentenols.