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• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

CuSO4 nanoparticles loaded onto poly (toluenesulfonic acid-formaldehyde)/polyethyleneimine composites: An efficient retrievable catalyst for A3/decarboxylative A3 reactions

Using polymeric composite incorporated transition metal nanoparticles to promote various organic reactions has been found as one of the most powerful strategies in organic synthesis. In this paper, CuSO4 nanoparticles (CuSO4 NPs) anc

Copper-based catalysts derived from salen-type ligands: Synthesis of 5-substituted-1: H-tetrazoles via [3+2] cycloaddition and propargylamines via A3-coupling reactions

Base-metal copper(ii) complexes derived from unsymmetrical salen-type ligands were designed and synthesized using ligands L1H to L4H in moderate yield. The synthesized unsymmetrical ligands L1H to L4H and the corresponding copper complexes (1-4) were characterized by UV-visible, IR and ESI-MS spectroscopic studies. Molecular structures of complexes 1, 2 and 4 were determined by X-ray crystallography. Copper complexes 1-4 were employed as catalysts for [3+2] cycloaddition and A3-coupling reactions. The mutual approach of salen-type ligands and metals via active participation of ligands allow to achieve the catalytic reactions. Reaction pathways were proposed and possible intermediate species during the catalytic cycle were successfully characterized by ESI-MS spectroscopic studies. This journal is

Cu0NPs@CMC: an efficient recoverable nanocatalyst for decarboxylative A3 and A3 couplings under neat condition

Abstract: Copper nanoparticles assembled on carboxymethylcellulose (Cu0NPs@CMC) were successfully synthesized and well characterized by FT-IR, SEM, EDS, TEM, XPS, and ICP-AES. The new prepared nanocatalyst was applied effectively as a heterogen

Chitosan-supported copper as an efficient and recyclable heterogeneous catalyst for A3/decarboxylative A3-coupling reaction

Chitosan-supported copper (chit@copper) based heterogeneous catalysts have been explored for A3-coupling and decarboxylative A3-coupling. The developed protocol employs low catalyst loading, solventless condition and easy work-up for

Zn(OTf)2-Mediated Expeditious and Solvent-Free Synthesis of Propargylamines via C-H Activation of Phenylacetylene

Zn(OTf)2-mediated expeditious and solvent-free synthesis of propargylamines via A3 coupling of aldehydes, amines, and phenylacetylene has been described. The described protocol proceeds effectively with variety of substituted benzaldehydes, enolizable aldehyde, and formaldehyde. Recyclability of the catalyst, low catalyst loading, and use of inexpensive catalyst are the key features of the present protocol.

Copper(II) carboxymethylcellulose (CMC-CuII) as an efficient catalyst for aldehyde-alkyne-amine coupling under solvent-free conditions

A novel and eco-friendly three-component reaction of aldehydes, amines, and alkynes (A3 coupling) catalyzed by a recoverable copper(ii) carboxymethylcellulose (CMC-CuII) catalyst has been developed, producing a diverse range of propargylamines under solvent-free conditions in good yields. The CMC-CuII catalyzed reaction is especially effective for reactions involving aromatic and aliphatic aldehydes. High catalytic activity was obtained in the presence of 5 mol% CMC-CuII without any other co-catalyst, additives, or bases under aerobic conditions. Moreover, the catalyst can be easily recovered and reused for at least four cycles without significant decrease in its catalytic activity.

Copper-catalyzed one-pot synthesis of propargylamines via C-H activation in PEG

An efficient and convenient three-component A3 coupling reaction of aldehyde, amine and alkyne via C-H activation with CuI alone as the catalyst in PEG is developed, providing a wide range of propargylamines with yields ranging from moderate to

A simple and economic synthesis of propargylamines by cuI-catalyzed three-component coupling reaction with succinic acid as additive

A practical and efficient method was developed for the synthesis of propargylamines in a one-pot procedure from aldehydes, amines, and alkynes by using CuI as catalyst and succinic acid as additive. By using this protocol, a wide range of propargylamines was obtained in high yields. CSIRO 2009.