117488-02-5Relevant articles and documents
Synthesis, NMDA receptor antagonist activity, and anticonvulsant action of 1-aminocyclobutanecarboxylic acid derivatives
Gaoni,Chapman,Parvez,Pook,Jane,Watkins
, p. 4288 - 4296 (2007/10/02)
A range of cis- and trans-3-substituted 1-aminocyclobutane-1-carboxylic acids has been synthesized and evaluated for antagonism at excitatory amino acid receptor sites and for anticonvulsant activity. Potent and selective antagonist activity at N-methyl-D
REGIOSPECIFIC ADDITIONS OF HYDRAZOIC ACID AND BENZYLAMINE TO 1-(ARYLSULFONYL)BICYCLOBUTANES. APPLICATION TO THE SYNTHESIS OF CIS AND TRANS 2,7-METHANOGLUTAMIC ACIDS
Gaoni, Yehiel
, p. 1591 - 1594 (2007/10/02)
Addition of hydrazoic acid or benzylamine to 1-(arylsulfonyl)bicyclobutanes introduces the nitrogen nucleophile at position 3 of the derived cyclobutane, even when a carboxyl derivative is present at this position as a second activating group.Precursors o