1174888-65-3Relevant academic research and scientific papers
PNA/DNA interstrand cross-links from a modified PNA base upon photolysis or oxidative conditions
Kim, Yongtae,Hong, In Seok
, p. 5054 - 5057 (2008)
PNA/DNA interstrand cross-links (ICLs) were observed when peptide nucleic acids (PNAs) containing modified thymine derivatives were hybridized with the complementary or one-base mismatched DNA upon photolysis or treatments of oxidative agent. PNA/DNA ICL formation provides a useful method for biological applications such as antisense technologies or PNA chips.
