117490-99-0

Basic information

• Product Name: 5-acetyl-4-{4-nitrophenyl}-6-methyl-2-(methylsulfanyl)-1,4-dihydropyridine-3-carbonitrile
• Synonyms: 5-acetyl-4-{4-nitrophenyl}-6-methyl-2-(methylsulfanyl)-1,4-dihydropyridine-3-carbonitrile
• CAS NO: 117490-99-0
• Molecular Formula: C₁₆H₁₅N₃O₃S
• Molecular Weight: 329.3736
• Mol File: 117490-99-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-acetyl-4-{4-nitrophenyl}-6-methyl-2-(methylsulfanyl)-1,4-dihydropyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-acetyl-4-{4-nitrophenyl}-6-methyl-2-(methylsulfanyl)-1,4-dihydropyridine-3-carbonitrile(117490-99-0)
• EPA Substance Registry System: 5-acetyl-4-{4-nitrophenyl}-6-methyl-2-(methylsulfanyl)-1,4-dihydropyridine-3-carbonitrile(117490-99-0)

Safety Data

• Hazardous Substances Data: 117490-99-0(Hazardous Substances Data)

Upstream product

• 29197-16-8 3-(4-nitrobenzylidene)pentane-2,4-dione 
• 7357-70-2 Cyanothioacetamide 
• 74-88-4 methyl iodide 
• 252001-57-3 6-methyl-5-acetyl-4-(4-nitrophenyl)-3-cyano-3,4-dihydropyridine-2-thione 
• 116736-39-1 5-Acetyl-2-mercapto-6-methyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3-carbonitrile; compound with piperidine 
• 117491-07-3 6-Oxy-2-methylthio-6-methyl-4-(p-nitrophenyl)-5-acetyl-3-cyano-1,4,5,6-tetrahydropyridine 

Relevant articles and documents

Synthesis and antiradical activity of 5-acetyl-2-alkylthio-4-aryl-6-methyl-1,4-dihydropyridine-3-carboxylic acid nitriles

The alkylation of 3-cyano-1,4-dihydropyridine-2(3H)-thiones or the condensation of an aromatic aldehyde, cyanothioacetamide, acetylacetone, and methyl iodide in the presence of piperidine has given a series of novel 5-acetyl-2-alkylthio-4-aryl-6-methyl-1,4-dihydropyridine-3-carboxylic acid nitriles. A compound was obtained from 3,5-di(tert-butyl)-4-hydroxybenzaldehyde in the molecule of which were combined the active part of the antioxidant ionol and a 1,4-dihydropyridine ring. It was found that, among the compounds synthesized, the highest antiradical activity occurred in a compound having two hydroxyl groups in the 4-phenyl substituent.