1174903-49-1

Basic information

• Product Name: 3-[[(2-fluorobenzyl)-methyl-amino]methyl]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one
• CAS NO: 1174903-49-1
• Molecular Weight: 314.319
• Mol File: 1174903-49-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[[(2-fluorobenzyl)-methyl-amino]methyl]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[[(2-fluorobenzyl)-methyl-amino]methyl]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one(1174903-49-1)
• EPA Substance Registry System: 3-[[(2-fluorobenzyl)-methyl-amino]methyl]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one(1174903-49-1)

Safety Data

• Hazardous Substances Data: 1174903-49-1(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 2845-82-1 5-(pyridin-4-yl)-3H-1,3,4-oxadiazol-2-one 
• 399-30-4 1-(2-fluorophenyl)-N-methylmethanamine 

Relevant articles and documents

Antimycobacterial activity of new 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-one derivatives. Molecular modeling investigations

3H-1,3,4-Oxadiazol-2-one derivatives were synthesized and tested for their in vitro antimycobacterial activity. Oxadiazolone derivatives showed an interesting antimycobacterial activity against the reference strain of Mycobacterium tuberculosis H37Rv. Molecular modeling investigations were performed and showed that the active compounds possess all necessary features to target the protein active site of the mycobacterial cytochrome P450-dependent sterol 14α-demethylase in the sterol biosynthesis pathway as the calculated free energy of binding were in agreement with the corresponding MIC values.