6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE, also known as ROX NHS ester, is a pure single isomer rhodamine dye linker containing an NHS ester group. It is designed to label primary amines (-NH2) of proteins, oligonucleotides, and other amine-containing molecules. This dye can serve as a substitute for Alexa Fluor 568 and Texas Red, offering a versatile and reliable alternative for various applications.
117491-83-5
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Basic information
- Product Name: 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE
- Synonyms: 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE;ROX NHS ester, pure 6- isomer;ROX NHS ester, 6- isomer
- CAS NO:117491-83-5
- Molecular Formula: C37H33N3O7
- Molecular Weight: 631.67382
- EINECS: N/A
- Product Categories: N/A
- Mol File: 117491-83-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in DMF, DMSO
- CAS DataBase Reference: 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE(CAS DataBase Reference)
- NIST Chemistry Reference: 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE(117491-83-5)
- EPA Substance Registry System: 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE(117491-83-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 117491-83-5(Hazardous Substances Data)
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117491-83-5 Usage
Uses
Used in Biochemical Research:6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE is used as a fluorescent probe for biochemical research, allowing for the visualization and tracking of amine-containing molecules such as proteins and oligonucleotides. Its ability to replace Alexa Fluor 568 and Texas Red makes it a valuable tool for researchers in various fields.
Used in Drug Development:
In the pharmaceutical industry, 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE is used as a labeling agent for drug development. By attaching the dye to drug molecules, researchers can monitor the distribution, metabolism, and interactions of the drug within biological systems, aiding in the optimization of drug design and efficacy.
Used in Diagnostic Imaging:
6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE is used as a contrast agent in diagnostic imaging, particularly in fluorescence imaging techniques. Its fluorescent properties enable the detection and visualization of specific biological processes or molecular targets, improving the accuracy and sensitivity of diagnostic procedures.
Used in Biosensors:
In the field of biosensors, 6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE is used as a signal transducer, converting biological recognition events into measurable fluorescent signals. This allows for the development of highly sensitive and specific biosensors for detecting various analytes, such as proteins, nucleic acids, or small molecules.
Used in Cell Biology:
6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE is used as a cell labeling agent in cell biology research. By labeling specific proteins or other cellular components, researchers can study cell structure, function, and dynamics, contributing to a better understanding of cellular processes and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 117491-83-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,4,9 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 117491-83:
(8*1)+(7*1)+(6*7)+(5*4)+(4*9)+(3*1)+(2*8)+(1*3)=135
135 % 10 = 5
So 117491-83-5 is a valid CAS Registry Number.
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6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE
