1174918-98-9

Upstream product

• 1516933-97-3 4,4,5,5-tetramethyl-2-(7-methyl-3-methyleneoct-6-en-1-yl)-1,3,2-dioxaborolane 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Downstream Products

• 106-25-2 Nerol 
• 1448722-25-5 (2R,3R,4R,5R)-1,3-[(S)-benzylidenedioxy]-5,9-dimethyl-5-vinyldec-8-ene-2,4-diol 
• 1448722-26-6 (2R,3R,4R,5S)-1,3-[(S)-benzylidenedioxy]-5,9-dimethyl-5-vinyldec-8-ene-2,4-diol 
• 1544322-48-6 (E)-1-(5-((E)-3,7-dimethylocta-2,6-dien-1-yl)-2,4-bis(methoxymethoxy)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 1544322-63-5 (E)-1-(3-((E)-3,7-dimethylocta-2,6-dien-1-yl)-2,4-bis(methoxymethoxy)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 1403229-22-0 1-(tert-butyl)-4-(3,7-dimethylocta-1,6-dien-3-yl)benzene 
• 1403229-20-8 1-(tert-butyl)-4-(3,7-dimethylocta-2,6-dien-1-yl)benzene 
• 93741-45-8 1-(tert-butyl)-4-(3,7-dimethylocta-2,6-dien-1-yl)benzene 

Relevant academic research and scientific papers

A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic Alcohols

A catalytic sequence for the diastereo- and enantioselective preparation of homoallylic alcohols with an adjacent quaternary (stereo)center is reported. The one-pot process relies on the use of a single (achiral or chiral) iridium complex to catalyze the concomitant isomerization of primary allylic alcohols and homoallylboronates into (chiral) aldehydes and allylboronates, respectively. In the same flask, a chiral Br?nsted acid is added next to engage the isomerization products into a stereocontrolled allylboration reaction. Structural variations have been performed on both the allylic alcohols and the homoallylboronates. This mild process affords an array of stereochemically congested and complex chiral secondary homoallylic alcohols in high yield, excellent diastereoselectivity, and usually high enantioselectivity.