1174936-40-3Relevant academic research and scientific papers
Preparation of novel compound and application of novel compound in cancer therapy
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, (2019/03/08)
The invention belongs to the field of biomedicine, and provides a method of designing and preparing a novel compound, and application of the novel compound in cell growth regulatory mechanisms and cancer treatment. The bioactivity test indicates that the
2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers
El Bakali, Jamal,Klupsch, Frederique,Guedin, Aurore,Brassart, Bertrand,Fontaine, Gaelle,Farce, Amaury,Roussel, Pascal,Houssin, Raymond,Bernier, Jean-Luc,Chavatte, Philippe,Mergny, Jean-Louis,Riou, Jean-Francois,Henichart, Jean-Pierre
scheme or table, p. 3434 - 3438 (2010/04/26)
The design and synthesis of 2,6-diphenylthiazolo[3,2-b][1,2,4]triazoles characterized by a large aromatic building block bearing cationic side chains are reported. These molecules are evaluated as telomeric G-quadruplex stabilizers and for their selectivi
