117523-29-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridinecarboxylic acid, 3-(phenylmethoxy)is utilized as a building block for the synthesis of various drug compounds due to its versatile chemical structure and pharmacological potential.
Used in Medication Development:
This chemical is employed as a potential candidate for the development of new medications, particularly for its anti-inflammatory, analgesic, and antipyretic properties, which can be beneficial in treating a range of conditions.
Used in Cancer Treatment Research:
2-Pyridinecarboxylic acid, 3-(phenylmethoxy)is studied for its potential role in the treatment of cancer, as it has been found to modulate cellular signaling pathways, which could contribute to the development of novel therapeutic approaches against the disease.

Upstream product

• 874-24-8 3-hydroxypyridine-2-carboxylic acid 
• 170689-52-8 3-benzyloxypyridine-2-carboxylic acid benzyl ester 

Downstream Products

• 203807-29-8 (N-(3-benzyloxypyridyl-2-carbonyl)-D-Ser-Pip-Gly-Sar-NMe-Val)2 (serine hydroxyl) dilactone 
• 603955-32-4 3-benzyloxypyridine-2-carbonyl chloride 

Relevant academic research and scientific papers

In pursuit of natural product leads: Synthesis and biological evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4- carboxylic acid (A-33853) and its analogues: Discovery of N-(2-benzoxazol-2- ylphenyl)benzamides as novel

The first synthesis and biological evaluation of antibiotic 31 (A-33853) and its analogues are reported. Initial screening for inhibition of L. donovani, T. b. rhodesiense, T. cruzi, and P. falciparum cultures followed by determination of IC50

Inhibitors of type I MetAPs containing pyridine-2-carboxylic acid thiazol-2-ylamide. Part 1: SAR studies on the determination of the key scaffold

Systematic SAR studies on the HTS hit pyridine-2-carboxylic acid thiazol-2-ylamide (PACT) analogues revealed that the scaffold of PCAT is indispensable for the inhibition of type I MetAP. For effective inhibition of the enzyme, the most suitable position to modify is the 3-position of the pyridine ring of PCAT, and the best substituents are those containing O or N atoms connected directly with the pyridine ring. These findings provide useful information for the design and discovery of more potent inhibitors of type I MetAPs.

Synthesis of key sandramycin analogs: Systematic examination of the intercalation chromophore

The preparation and examination of 2-22 constituting a systematic study of the chromophore of sandramycin (1) are detailed. Fluorescence quenching studies were used to establish binding constants for 1-24 within calf thymus DNA, within a single high affin