117554-70-8

Basic information

• Product Name: 11-(Benzamidomethyl)-12-(nicotinamidomethyl)-12H-benzophenothiazine

Upstream product

• 135-19-3 β-naphthol 
• 117554-59-3 N-(2-Phenylamino-naphthalen-1-ylmethyl)-benzamide 
• 69025-33-8 N-((2-hydroxynaphthalen-1-yl)methyl)benzamide 
• 6282-02-6 N-(hydroxymethyl)benzamide 
• 3569-99-1 N-hydroxymethylnicotinamide 
• 117554-62-8 N-(12H-Benzo[b]phenothiazin-11-ylmethyl)-benzamide 

Relevant articles and documents

Synthesis of 11,12-Bis(aryl-amido/imidoalkyl)-12H-benzophenothiazines as Potential Anthelmintics

Condensation of N-(hydroxyalkyl)aryl-amides/imides (I) with β-naphthol gives 1-(aryl-amido/imido-alkyl)-2-naphthols (II) which on reaction with aniline in the presence of Zn dust afford 1-(aryl-amido/imido-alkyl)-N-aryl-2-naphthylamines (III).Heating of III in the presence of sulphur and iodine furnishes 11-(aryl-amido/imido-alkyl)-12-H-benzophenothiazines (IV).Condensation of IV with N-hydroxyalkyl-amides/imides affords 11,12-bis(aryl-amido/imido-alkyl)-12H-benzophenothiazines (V).Some of the compounds show anthelmintic activity ranging from 5 to 95percent.