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N-Cbz-4-Methyl-5-oxooxazolidine, also known as 4-Methyl-5-oxooxazolidine-2-carboxylic acid benzyl ester, is a chemical compound that plays a significant role in organic synthesis. It is a key intermediate in the production of pharmaceuticals, particularly for the synthesis of peptide-based drugs. N-Cbz-4-Methyl-5-oxooxazolidine is widely recognized for its utility as a protecting group for amino acids during peptide synthesis, as it can be easily removed under mild conditions. Moreover, its capacity to undergo a range of chemical transformations renders it a versatile building block in the synthesis of complex molecules. N-Cbz-4-Methyl-5-oxooxazolidine holds an important position in the field of medicinal chemistry, being essential for the development of new drugs and therapeutic agents.

117558-24-4

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117558-24-4 Usage

Uses

Used in Pharmaceutical Synthesis:
N-Cbz-4-Methyl-5-oxooxazolidine is used as a key intermediate in the synthesis of peptide-based drugs. Its role is crucial in the development of new pharmaceuticals and therapeutic agents.
Used as a Protecting Group in Peptide Synthesis:
In the field of peptide synthesis, N-Cbz-4-Methyl-5-oxooxazolidine serves as an effective protecting group for amino acids. It allows for the prevention of unwanted side reactions during the synthesis process and can be conveniently removed under mild conditions, ensuring the purity and functionality of the final peptide product.
Used in Organic Synthesis:
N-Cbz-4-Methyl-5-oxooxazolidine is also utilized as a versatile building block in organic synthesis. Its ability to undergo various chemical transformations makes it an indispensable tool for creating complex molecules, which can be further used in the development of innovative pharmaceuticals and other chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 117558-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,5,5 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 117558-24:
(8*1)+(7*1)+(6*7)+(5*5)+(4*5)+(3*8)+(2*2)+(1*4)=134
134 % 10 = 4
So 117558-24-4 is a valid CAS Registry Number.

117558-24-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-?Oxazolidinecarboxyli?c acid, 4-?methyl-?5-?oxo-?, phenylmethyl ester

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:117558-24-4 SDS

117558-24-4Downstream Products

117558-24-4Relevant academic research and scientific papers

SYNTHESIS OF DERIVATIVES OF OXAZOLIDIN-5-ONES

Katkevich, M.Yu.,Sile, D.E.,Slavinska, V.A.,Liepinya, I.M.,Popelis, Yu.Yu.

, p. 100 - 102 (2007/10/02)

A method has been developed for the synthesis of derivatives of oxazolidin-5-one by the reaction of the corresponding N-benzyloxycarbonylaminoacid with formaldehyde in the presence of formic acid.Yields of derivatives of 3-benzyloxycarbonyloxazolidin-5-on

Reductive Radical Decarboxylation of Amino-acids and Peptides

Barton, Derek H. R.,Herve, Yolande,Potier, Pierre,Thierry, Josiane

, p. 1298 - 1299 (2007/10/02)

Radicals generated from N-protected α-amino-acids by photolysis of their N-hydroxypyridine-2-thione esters at room temperature are efficiently quenched by t-butyl thiol to give decarboxy-acids; comparable reactions have been carried out on the side chain carboxy groups of suitable protected aspartic and glutamic acids.

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