1175604-27-9Relevant academic research and scientific papers
Reductive ring-opening of phthalan and isochroman: Application to the stereoselective synthesis of tetrahydroisoquinolines and tetrahydrobenzazepines
Garcia, Daniel,Foubelo, Francisco,Yus, Miguel
experimental part, p. 2893 - 2903 (2010/08/05)
The reaction of the dianionic intermediates 2a,b resulting from the lithiation of phthalan (la) and isochroman (lb) with chiral N-tert-butylsulfinyl aldimines 9 in the presence of ZnMe2 gave, after hydrolysis, N-tert-butylsulfinyl amino alcohol
Stereoselective synthesis of 3-substituted tetrahydroisoquinolines from phthalan and chiral N-sulfinylimines
García, Daniel,Moreno, Benjamín,Soler, Tatiana,Foubelo, Francisco,Yus, Miguel
scheme or table, p. 4710 - 4713 (2011/02/28)
The reaction of the dianionic intermediate [resulting from the reductive opening of phthalan (1) with lithium] with chiral N-tert-butylsulfinyl aldimines 3 in the presence of ZnMe2 gives, after hydrolysis, N-tert-butylsulfinyl amino alcohols 4
